{ "_id": "6a227e32cd65a98ecbd503d6", "Package": "medoutcon", "Title": "Efficient Natural and Interventional Causal Mediation Analysis", "Version": "0.2.4", "Authors@R": "c(\nperson(\"Nima\", \"Hejazi\", email = \"nh@nimahejazi.org\",\nrole = c(\"aut\", \"cre\", \"cph\"),\ncomment = c(ORCID = \"0000-0002-7127-2789\")),\nperson(\"Iván\", \"Díaz\", email = \"ild2005@med.cornell.edu\",\nrole = \"aut\",\ncomment = c(ORCID = \"0000-0001-9056-2047\")),\nperson(\"Kara\", \"Rudolph\", email = \"kr2854@cumc.columbia.edu\",\nrole = \"aut\",\ncomment = c(ORCID = \"0000-0002-9417-7960\")),\nperson(\"Philippe\", \"Boileau\", email = \"philippe_boileau@berkeley.edu\",\nrole = \"ctb\",\ncomment = c(ORCID = \"0000-0002-4850-2507\")),\nperson(\"Mark\", \"van der Laan\", email = \"laan@berkeley.edu\",\nrole = c(\"ctb\", \"ths\"),\ncomment = c(ORCID = \"0000-0003-1432-5511\"))\n)", "Maintainer": "Nima Hejazi ", "Description": "Efficient estimators of interventional (in)direct effects\nin the presence of mediator-outcome confounding affected by\nexposure. The effects estimated allow for the impact of the\nexposure on the outcome through a direct path to be\ndisentangled from that through mediators, even in the presence\nof intermediate confounders that complicate such a\nrelationship. Currently supported are non-parametric efficient\none-step and targeted minimum loss estimators based on the\nformulation of Díaz, Hejazi, Rudolph, and van der Laan (2020)\n. Support for efficient estimation\nof the natural (in)direct effects is also provided, appropriate\nfor settings in which intermediate confounders are absent. The\npackage also supports estimation of these effects when the\nmediators are measured using outcome-dependent two-phase\nsampling designs (e.g., case-cohort).", "Remotes": [ "github::tlverse/hal9001", "github::tlverse/sl3" ], "License": "MIT + file LICENSE", "URL": "https://github.com/nhejazi/medoutcon", "BugReports": "https://github.com/nhejazi/medoutcon/issues", "Encoding": "UTF-8", "VignetteBuilder": "knitr", "RoxygenNote": "7.3.1", "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libuv1-dev\nlibxml2-dev", "Repository": "https://ictml-project.r-universe.dev", "Date/Publication": "2025-07-07 18:25:49 UTC", "RemoteUrl": "https://github.com/nhejazi/medoutcon", "RemoteRef": "HEAD", "RemoteSha": "e40d519cce0e674e4a2f1ba853c6d32908c7f9b0", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-05 07:22:20 UTC", "User": "root" }, "Author": "Nima Hejazi [aut, cre, cph] (ORCID:\n),\nIván Díaz [aut] (ORCID: ),\nKara Rudolph [aut] (ORCID: ),\nPhilippe Boileau [ctb] (ORCID: ),\nMark 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